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Flesinoxan is a potent, selective 5-hydroxytryptamine 1A (5-HT1A) receptor agonist used for pharmacological research. Supplied as a high-purity solid, it is suitable for in vitro and in vivo studies when handled and stored per recommended conditions.
Potent, high-affinity 5-HT1A receptor agonist.
High purity suitable for research applications.
Soluble in DMSO; in vivo formulations documented.
Stable under recommended storage conditions.
Available in small research-scale pack sizes.
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PF-562271 Besylate is the benzenesulfonate salt of PF-562271 which is a potent ATP-competitive reversible inhibitor of FAK with IC50 of 1 5 nM 10-fold less potent for Pyk2 than FAK and 100-fold selectivity against other protein kinases except for some CDKs Phase 1
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CUDA is a research-grade small-molecule inhibitor of soluble epoxide hydrolase (sEH) used in biochemical and cellular studies to probe sEH and PPAR-alpha pathways. It is supplied as a crystalline solid (CAS 479413-68-8) with molecular formula C19H36N2O3 and molecular weight 340.50 g/mol.
Potent sEH inhibitor with IC50 = 11.1 nM (mouse) and 112 nM (human).
High purity by HPLC (approximately 99.8%).
Supplied in small solid quantities suitable for assay development and cellular studies.
Soluble in common organic solvents for stock solution preparation.
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Guanidine-d5 (hydrochloride) is the deuterium labeled Guanidine hydrochloride. Guanidine hydrochloride (Guanidinium chloride) is a strong chaotrope and also a strong denaturant of proteins.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules largely as tracers for quantitation during the drug development process.
Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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